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cyclin-dependent kinase
(redirected from Cyclin dependent kinases)

    Also found in: Medical, Wikipedia 0.03 sec.
cyclin-dependent kinase [¦sī·klin di¦pen·dənt ′kī‚nās]
(cell and molecular biology)
A family of kinases that, once activated by cyclin, regulate the cell cycle by adding phosphate groups to a variety of protein substrates that control processes in the cycle. Abbreviated Cdk.
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One group of these novel compounds works by inhibiting Cyclin Dependent Kinases (CDK), drug targets that control cancer cell division.
United States patent granted to Cyclacel for cyclin dependent kinase ... by BIOTECH Patent News
The Company remains on track with enrollment of the Phase IIb, multi-center, randomized, double-blinded APPRAISE trial which is evaluating the efficacy and safety of the investigational drug seliciclib (CYC202), an orally-available molecule that targets cyclin dependent kinases (CDKs), as a third-line treatment in patients with non-small cell lung cancer (NSCLC).
Cyclacel Pharmaceuticals Reports Third Quarter 2006 Financial Results by Business Wire
Nasdaq: CYCC) announced today that the company is beginning a Phase IIb, multi-center, randomized, double-blinded trial to evaluate the efficacy and safety of the investigational drug seliciclib (CYC202), an orally available molecule that targets cyclin dependent kinases (CDKs), as a third line treatment in patients with non-small cell lung cancer (NSCLC).
Cyclacel Begins a Phase IIb Randomized Trial of Seliciclib for ... by Business Wire
 
 
 
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