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cyclin-dependent kinase

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
cyclin-dependent kinase [¦sī·klin di¦pen·dənt ′kī‚nās]
(cell and molecular biology)
A family of kinases that, once activated by cyclin, regulate the cell cycle by adding phosphate groups to a variety of protein substrates that control processes in the cycle. Abbreviated Cdk.


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13) p27 pathway p27(KIP1) is a member of the CIP1/KIP1 family of cyclin-dependent kinase inhibitors and is a potential tumor suppressor gene.
EXPERIMENTAL DESIGN: HCC cells were treated with vitamin K2 and the expression of several growth-related genes including cyclin-dependent kinase inhibitors and cyclin D1 was examined at the mRNA and protein levels.
0849337747 Inhibitors of cyclin-dependent kinases as anti-tumor agents.
 
 
 
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