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cyclin
(redirected from Cyclins)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
cyclin [′sī·klin]
(cell and molecular biology)
Any member of a family of proteins that regulate the cell cycle and whose cellular levels rise steadily until mitosis, then fall abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus toward mitosis.


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Restoring the miR-26a stopped the cancerous cells from creating two molecules called cyclins that are used in cell replication, effectively preventing the cells from multiplying.
Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down regulation of cyclins.
Cyclin-dependent kinases form complexes with proteins called cyclins that tightly regulate the progression of the series of steps in the cell cycle by activating and inactivating proteins by phosphorylation, including proteins that act as "brakes" on cell cycle progression and cell proliferation.
 
 
 
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