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cyclin |
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cyclin [′sī·klin] (cell and molecular biology) Any member of a family of proteins that regulate the cell cycle and whose cellular levels rise steadily until mitosis, then fall abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus toward mitosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 0]-synchronized cells expressed low levels of cyclins A and D1 and hypophosphorylated retinoblastoma (RB), whereas [G. The discovery of CDKs and cyclins and their role in checkpoint control of the cancer cell cycle has been honored with the 2001 Nobel Prize for Medicine and Physiology. When cyclins bind to CDK molecules, "this complex activates a bunch of proteins," Elledge says. |
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