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(organic chemistry)
C4H8 An alicyclic hydrocarbon, boiling point 11°C; synthesized as a condensable gas; used in organic synthesis. Also known as tetramethylene.



(also tetramethylene), an alicyclic hydrocarbon; a colorless gas, with a weak odor, a boiling point of 12.9°C, and a density of 0.703 g/cm3 (at 0°C).

Cyclobutane is insoluble in water but is soluble in alcohol, acetone, and ether. It has all the chemical properties characteristic of cycloparaffins. It may be obtained from 1,4-dibromo butane and by other methods. Octafluorocyclobutane, C4F8, produced by the dimerization of tetrafluoroethylene is used in industry as a freon.

References in periodicals archive ?
Reagentas cyclobutane pyrimidine dimers determination after UV-irradiation preliminary points to 1 Coll .
It is an excellent photostabilizer, provides in-vivo SPF boosting by 50% for both organic and inorganic sunscreens and protects skin by inhibiting up-stream ROS cascade, namely, NADPH oxidase inhibitor, Chelator and inhibitor of cyclobutane dimer formation.
Firstly, UVR causes DNA mutations in skin cells via the formation of cyclobutane pyrimidine dimers (Rochette et al.
Cyclobutane is condensed to aromatic rings such as benzene, naphthalene, anthracene, and pyrene and may have different substituents such as alkyl, alkoxy, alkylthio, and aryl groups.
8 dimethyl, smoking area cyclobutane #2--north wing exit * The emission rate from the different sources is normalized to the rate of the indoor source o-PDCH.
The human DNA polymerase i (hPoln) specializes in repairing UV-induced cyclobutane pyrimidine dimers (CPD) formed from adjacent thymine bases by pairing the corresponding adenines during a process known as translesion synthesis (TLS).
The reason why we choose cinnamic acid as side chains is that the bio-based cinnamate groups are hydrophobic, and they could show [2 + 2] cyclobutane formation between two adjacent cinnamate groups under ultraviolet light (UV) irradiation at [lambda] > 280 nm (18), (19).
EGCG also inhibits the formation of cyclobutane pyrimidine dinners, a known source of UVR-induced DNA damage.
We also showed that treatment of GTP to human skin prevents UVB-induced cyclobutane pyrimidine dimers formation, which are considered to be mediators of UVB-induced immune suppression and skin cancer induction.
His design employs either polyesters (more sustainable due to access to bio-based raw materials) or poly-imides (for high-temperature applications) that are functionalized with cyclobutane substrates through the photochemistry of maleic anhydrides, which undergo a [2[Plus]2] cycloaddition reaction to form cyclobutanes when exposed to one wavelength of light and the reverse when exposed to another.
Higher cyclobutane pyrimidine dimer and (6-4) photoproduct yields in epidermis of normal humans with increased sensitivity to ultraviolet B radiation.
Artificial and solar UV radiation induces strand breaks and cyclobutane pyrimidine dimers in Bacillus subtilis spore DNA.