cyclooxygenase

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cyclooxygenase

[‚sī·klō′äks·ə·jə‚nās]
(biochemistry)
An enzyme that catalyzes the conversion of arachidonic acid into prostaglandins.
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References in periodicals archive ?
Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: Meta-analysis of randomized trials.
4-8) Recently, additional new markers including CD44, platelet-derived growth factor receptor [alpha] (PDGFR-[alpha]), and cyclooxygenase 2 (COX-2) have been proposed as potential prognostic indicators.
9) Cyclooxygenase 2 is not expressed in most tissues, but has been shown to increase during the inflammatory response through interactions with agents such as growth factors and cytokines.
Cyclooxygenase 2 is known to be a target gene of the ras oncogene.
Inhibition of heat-shock protein 70 induction in intestinal cells overexpressing cyclooxygenase 2.