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cyclophilin
(redirected from Cyclophilin D)

    Also found in: Wikipedia 0.01 sec.
cyclophilin [‚sī·kə′fil·ən]
(biochemistry)
An abundant cytoplasmic protein that catalyzes cis-trans isomerizations; it has a high affinity for the immunosuppressive drug cyclosporin A.
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That experiment, combined with other studies using mice lacking cyclophilin D, indicated that amyloid-beta and cyclophilin D may be partners in crime, working together to cause mitochondria to rupture and release their deadly contents into the cell.
Mitochondria gone bad: problems in the cell's energy factories power ... by Beil, Laura / Science News
 
 
 
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