cyclophilin

(redirected from Cyclophilin D)
Also found in: Medical.

cyclophilin

[‚sī·kə′fil·ən]
(biochemistry)
An abundant cytoplasmic protein that catalyzes cis-trans isomerizations; it has a high affinity for the immunosuppressive drug cyclosporin A.
References in periodicals archive ?
Simon Kerr, chief executive officer, Cypralis, said, "Cyprolides are a new class of fully synthetic cyclophilin inhibitors that are potent inhibitors of cyclophilin D and protect against opening of the mitochondrial permeability transition pore.
Cyclophilin D inhibitors for treating human conditions such as ischemia/reperfusion injury, trauma and neurodegenerative diseases.