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cyclophilin
(redirected from Cyclophilins)

    Also found in: Wikipedia 0.01 sec.
cyclophilin [‚sī·kə′fil·ən]
(biochemistry)
An abundant cytoplasmic protein that catalyzes cis-trans isomerizations; it has a high affinity for the immunosuppressive drug cyclosporin A.
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The researchers say that they analysed liver cells to determine which variant of cyclophilins is critical for hepatitis C virus replication, and found that blocking cyclophilin A leads complete inhibition of virus replication.
Protein key to hepatitis C virus replication identified by Asian News International
Cyclophilins are a family of enzymatic proteins that assist in the folding and transport of other proteins synthesized within a cell.
SCYNEXIS REPORTS SCY-635 POSITIVE SINGLE AGENT RESULTS by Biotech Business
Thus, 10 cyclophilins wind up facing outward, with 10 cyclosporins sandwiched between them.
Cyclosporin-protein complex controls genes by Pennisi, Elizabeth / Science News
 
 
 
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