ALS-008176 is an orally bioavailable prodrug of the RSV replication inhibitor ALS-008112, a cytidine
WithinRSV , our development program includes the cytidine
nucleoside analog inhibitor ALS-008176.
Cellular differentiation, cytidine
analogs and DNA methylation.
Exposure of cells to 20 [micro]M EGCG, 60 [micro]M EA, and 100 [micro]M RA significantly lowered the incorporation of radiolabeled cytidine
to 45%, 62%, and 46% of control values, respectively (Fig.
A mouse monoclonal antibody against 5-methyl cytidine
Citicoline is the generic name for CDP-choline (choline cytidine
5'-pyrophosphate), an organic molecule produced endogenously and found in all living cells.
The proteins, known as APOBEC cytidine
deaminases, cause clusters of mutations that can outnumber all others associated with cancer, say the researchers.
We purchased 2'-deoxycytidine (dC), 2'-deoxyguanosine (dG), 2'-deoxyadenosine (dA), thymidine (T), 2'-deoxyinosine (dI), cytidine
(C), guanosine (G), adenosine (A), uridine (U), inosine (I), and 5-methyl-2'deoxycytidine (5-mdC) from Sigma-Aldrich, and 5-hydroxymethyl-2'-deoxycytidine (5-hmdC) from Berry & Associates.
2_110 13 Cytidine
deaminase HmC4778_234 14 Fasciclin domain-containing protein HmSNP4691_183 14 Heat shock protein 70 Hm3Dl0_1 15 Hemocyaninlike HmC4791_1099 15 Hypothetical protein HmC1449_847 16 Insulinlike growth factor binding protein 7 HmC18774_676 16 3-Hydroxy-3-methylglutaryl-CoA HmC22449_261 16 Protein disulfide isomerase HmC3835_411 16 Sorbitol dehydrogenase HmC45_3002 16 Hillarin HmC6061_1289 16 Phosphoglycerate mutase 2 HmC929_2563 17 Hexokinase Hm3B4_2 18A Ribosomal protein 1 Hm3B4_7 18A Ribosomal protein l HmC253_1545 18C PDZ and LIM domain protein Zasp Hmid2044 18C Hemocyanin Isoform 1 HmidILL2.
emtricitabine (FTC)--a cytidine
analogue very similar to 3TC--that is combined with TDF in a fixed-dose combination or with the addition of EFV as a triple-drug combination pill.
5-Methylcytidine (5-MeCyd) is cytosine modified by methylation on the fifth position of the cytidine
The guanosine at position 15719 in the reference fragment was replaced by cytidine
in our samples.