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cytochrome |
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cytochrome (sī`təkrōm'), protein containing heme (see coenzyme biotin, is a member of the B complex; it was first isolated in 1935 from dried egg yolk, and its structure was established in 1942. Biotin is usually found attached to a lysine residue in certain enzymes, where it participates in reactions involving the transfer of carboxyl ..... Click the link for more information. ) that participates in the phase of biochemical respiration called oxidative phosphorylation phosphorylation, chemical process in which a phosphate group is added to an organic molecule. In living cells phosphorylation is associated with respiration , which takes place in the cell's mitochondria, and photosynthesis, which takes place in the chloroplasts. ..... Click the link for more information. . Cytochromes act as carriers of hydride ions (sometimes considered to be the equivalent of electron pairs) in the series of complex enzymes known as the electron transport chain. As the hydride ions or their equivalent travel along the electron transport chain, each cytochrome is in turn reduced (accepts a hydride ion or pair of electrons) and then oxidized (donates the hydride ion or pair of electrons to the next acceptor in the chain); in the process the iron atom in the cytochrome heme shuttles between the ferrous and ferric states. The cytochromes were discovered in 1886. cytochromeAny of a group of cell proteins (hemoproteins) that serve a vital function in the transfer of energy within cells. Hemoproteins are linked to a nonprotein, iron-bearing component (a heme group), which can undergo the reversible oxidation-reduction reactions that yield energy for the cell. Cytochromes are subdivided into three classes depending on what wavelengths of light they absorb. At least 30 different cytochromes have been identified. |
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The virus isolate was confirmed as LBV by antigenic and genetic characterization, and the mongoose was identified as Atilax paludinosus by mito-chondrial cytochrome b sequence analysis. The AmpliChip CYP 450, which was co-developed with Affymetrix, can detect polymorphisms in cytochrome P450, an enzyme related to drug metabolism. Toluene induces expression of cytochrome P450 2E1 (CYP2EI), an enzyme involved in its own metabolism and that of other protoxicants, including some procarcinogens. |
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