cytomegalovirus

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cytomegalovirus

(sī'təmĕg'əlōvī`rəs), member of the herpesvirus family that can cause serious complications in persons with weakened immune systems and infants. A common virus, it is estimated that up to 80% of Americans carry cytomegalovirus by the time they reach adulthood. Most experience no symptoms or mild symptoms such as enlarged lymph nodes, low fever, and fatigue that may or may not be noticed. Cytomegalovirus is present in body fluids (saliva, semen, cervical secretions, and urine) and can be spread from person to person by sexual contact, kissing, or the sharing of food. It can also be transmitted from mother to fetus. The virus usually remains dormant in the body, but it can reactivate and cause serious symptoms in immunologically suppressed patients, such as those with AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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, or in infants whose immune systems are not yet fully developed. An estimated 25% of AIDS patients experience CMV infection, often in the form of a viral retinitis that can lead to blindness. Infants can become infected before birth when the mother becomes infected or experiences a recurrence during pregnancy. In a newborn, CMV can be life-threatening, and it can lead to later complications such as cerebral palsy, blindness, hearing problems, mental retardation, and learning disabilities. The antiviral drugs foscarnet and ganciclovir are used to keep active infections under control.

cytomegalovirus

[¦sīd·ō¦meg·ə·lō′vī·rəs]
(virology)
An animal virus belonging to subgroup B of the herpesvirus group; causes cytomegalic inclusion disease and pneumonia.
References in periodicals archive ?
Valganciclovir (Valcyte[R]) is an FDA-approved drug used to treat cytomegalovirus infection.
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FermaVir has licensed the technology produced in Professor McGuigan's laboratory for the use in treatment in Shingles and Cytomegalovirus infections.
Among FermaVir's other lead drug candidates are powerful antiviral compounds with a new mechanism of action to treat Cytomegalovirus infections, another potentially debilitating condition caused by a member of the herpes family of viruses, which can cause blindness and frequently afflicts patients with compromised immune systems.
OTC BB: FMVR), a developer of new drug treatments for the treatment of Shingles and Cytomegalovirus infections, will present its progress and development plans at the Rodman & Renshaw Techvest 7th Annual Healthcare Conference in New York City, a high-profile forum for institutional investors and other professionals in the worldwide biotechnology industry.
Seroepidemiology of cytomegalovirus infection in and around Chandigarh.
Quantification of plasma cytomegalovirus DNA by polymerase chain reaction is a non-invasive method of supporting the diagnosis and can be used to monitor the treatment of cytomegalovirus infection in the immunocompetent.