cohesive end

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cohesive end

[kō′hē·siv ‚end]
(biochemistry)
References in periodicals archive ?
Work over the last 10 years, pioneered in large part in the Faculty of Medicine 'n' Dentistry, revealed that the enzyme PNKP plays a critical role in the repair of broken DNA ends produced by radiation and other agents.
Nevertheless, erroneous or abortive topoisomerase activity can result in persistent DNA strand breaks with the enzyme covalently attached to 3 or 5 DNA ends by a phosphotyrosyl bond, an anomalous structure that can compromise cell survival and/or genome integrity with the consequent implications in tumourigenesis.
If my brother's DNA ends up in the database, and he's forfeited his privacy rights by becoming a convicted felon," says Stephen Mercer, a Maryland Defense attorney, "has he also forfeited my privacy rights as a wholly innocent family member?
Using a linker that attaches an identification tag of known sequence to the DNA ends processed by the SURVEYOR Nuclease, SEAL generates a library of genetic variations present within a DNA sample relative to a reference sample, allowing recognition of both the sequence of the variant nucleotide and the sequence context of the mutation.
In reality, most transformed DNA ends up with multiple copies of the foreign gene, incomplete genes and/or gene fragments.
Our new system allows for visualizing DNA ends at the site of a double-stranded break in living cells.