DNA microarray

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DNA microarray

[¦dē¦en¦ā ′mī·krō·ə‚rā]
(cell and molecular biology)
A microscopic spot containing identical single-stranded polymeric molecules of deoxyribonucleotides (DNAs), usually oligonucleotides or complementary DNAs, attached to a solid support (such as a membrane, a polymer, or glass) used to simultaneously analyze the expression levels of the corresponding genes.
References in periodicals archive ?
5 SuppliersEi Role in Improving Data Sharing for DNA Microarrays 116
The book is divided into 15 chapters that can be broadly grouped under DNA microarrays, antibody microarrays and immunoassays, and methods to optimize sample quality as well as the resulting data.
Bochner's next invention came during the genomics era, when DNA microarrays allowed scientists to measure the expression of thousands of genes simultaneously.
The primary market for DNA microarrays remains academia, although genotyping and gene expression applications have made inroads in pharmaceutical labs.
A DNA chip, or DNA microarray, is a small glass slide that can reveal the presence or absence of particular DNA sequences in a sample.
DNA microarrays are microchips which are capable of scrutinising the activity of hundreds of genes at once - dramatically speeding up the pace of research.
Mergen Limited (San Leandro, CA), a leader in oligo-based DNA microarray technology, has entered into an agreement with Oxford Gene Technology resolving the patent infringement litigation between the companies.
Pantano indicates that research on coatings for DNA microarrays is driven by the need to put more spots on each slide so that more potential drugs or genes can be tested at once.
The use of DNA microarrays is central to the new functional genomic approach being developed by several research groups at the institute and will allow scientists to study the expression of all genes in a bacterium in a single experiment--4290 genes in the case of E.
DNA microarrays are being influenced by next-generation sequencing applications, as well as exciting new applications in rapid DNA analysis and diagnostics.
Editors Moretti and Rizzo (no affiliations listed) have collected research in the field on the use of oligonucleotides for detecting complementary DNA and RNA such as in DNA microarrays and the synthesis of artificial genes.
Based in Witterswil, Switzerland, Zeptosens, a 1998 spin-off of Novartis, sells the ZeptoMARK protein microarrays, SensiChip DNA microarrays and SensiChip DNA microarray system based on fluorescence detection on the surface of a planar optical waveguide.