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hybridization probe |
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hybridization probe [‚hī·brəd·ə′zā·shən ′prōb] (cell and molecular biology) A small molecule of deoxyribonucleic acid or ribonucleic acid that is radioactively labeled and used to identify complementary nucleic acid sequences by hybridization. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| A multiplexed array was fabricated by distributing up to 18 different microsphere sensors into the optical fiber array with species-specific 50-mer DNA probes corresponding to 6 BWAs of interest (Bacillus anthracis, Yersinia pestis, Francisella tularensis, Brucella melitensis, Clostridium botulinum, and vaccinia virus) and 1 BWA simulant, Bacillus thuringiensis kurstaki, with each organism represented by at least 2 probe sequences (online Appendix Table 1). The alliance also includes the development of highly sensitive, selective and portable detection systems that combine Nanosphere's proprietary nanoparticle DNA probe technology with Takara's proprietary ICAN(TM) isothermal gene amplification technology. Hybriscan technology" is a DNA probe that detects infectious organisms in blood. |
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