DNA

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DNA:

see nucleic acidnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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DNA (deoxyribonucleic acid)

See GENETICS.

DNA

(biochemistry)

DNA

deoxyribonucleic acid; a nucleic acid that is the main constituent of the chromosomes of all organisms (except some viruses). The DNA molecule consists of two polynucleotide chains in the form of a double helix, containing phosphate and the sugar deoxyribose and linked by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA is self-replicating, plays a central role in protein synthesis, and is responsible for the transmission of hereditary characteristics from parents to offspring

DNA

(1) See Windows DNA.

(2) (Digital Network Architecture) Introduced in 1978, it was Digital's umbrella term for its enterprise network architecture based on DECnet.
References in periodicals archive ?
Administration of Keytruda is much, much more effective in those people who have DNA repair mutations," he added.
What intrigues us is that only a handful of favorable genetic changes were required to enable dramatically accelerated DNA repair, which is how the E.
Through this work, the research team identified three genes responsible for a multi-protein complex, called SMC5/SMC6/MAGE, which regulates DNA repair and the control of cell division.
While they were originally designed to enhance the DNA damaging effects of chemotherapy and radiotherapy on cancer cells, where part of the DNA repair mechanism was already damaged, we are seeing they could be used to treat a wider range of cancers than previously thought.
A recent study on human lymphocytes by Janssen et al (20) found DNA repair activity of hOGG1 to be independent of the Ser326Cys variant.
It is the first time that genes involved in DNA repair have been identified as potential markers for a patient's response to therapy.
Women tested were also more likely to get breast cancer if they were older, had a family history of breast cancer, had not breastfed and had lower DNA repair capacity.
professional ambassadors), can be shown to have DNA repair levels assayed in serum proteins that increase their clinical responses when treated with the DNA repair enhancer, quinic acid (Quinmax[TM]).
I propose an explanation of these observations in terms of second-order selection of hypermutable (mutator) alleles based on alterations in DNA repair genes.
It carries information on such topics as genetics, cell signaling, cell cycle and DNA repair, diagnostics, apoptosis, animal models, antiogenesis, cancer therapy, and epidemiology and prevention.
These cell lines were then used to study phenotypical changes affected by the mutations, including DNA repair by whole cell extracts and the accumulation of oxidative DNA damage in genomic DNA of cells after exposure to oxidative stress.
ValiGen partners with pharmaceutical and agricultural companies to derive commercial value from its genomics technologies, which provide a continuum of capability from raw profiling of phenotypes to in vivo target validation using its proprietary chimeraplasty DNA repair technology.