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DNA vaccine
(redirected from DNA vaccination)

   Also found in: Medical, Wikipedia 0.01 sec.
DNA vaccine [¦de¦en¦ā vak′sēn]
(immunology)
A type of noninfectious vaccine that directly injects deoxyribonucleic plasmids that express antigens of interest, resulting in foreign protein expression within the cells of the vaccine; however, the vaccine itself is unable to replicate.


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While research to date has found DNA vaccines to be a safe option, the long-term safety associated with DNA vaccination remains to be seen.
Researchers from a number of countries review the literature on such aspects as anti-ergotypic regulatory T-cells, regulatory mechanisms induced by t-cell vaccination in humans, peptide and DNA vaccination in experimental allergic encephalomyelitis (EAE) and multiple sclerosis, and regulatory anti-T-cell antibodies induced by T-cell vaccination.
This is the first demonstration of a beneficial effect of DNA vaccination in a clinical trial of autoimmune disease.
 
 
 
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