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dehydroascorbic acid
(redirected from Dehydroascorbate)

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dehydroascorbic acid [dē¦hī·drō·ə¦skȯr·bik ′as·əd]
(organic chemistry)
C6H6O6A relatively inactive acid resulting from elimination of two hydrogen atoms from ascorbic acid when the latter is oxidized by air or other agents; has potential ascorbic acid activity.
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In 1969 the National Cancer Institute showed that oxidized vitamin C (also known as dehydroascorbate or DHA) safely killed cancer cells in vitro but that glucose counteracted the DHA.
Vitamins vs. chemotherapy and radiation for cancer therapy by Houston, Reagan / Townsend Letter
In fact free-radicals presence induce ascorbate oxidation to give dehydroascorbate, which if not reduced by GSH is irreversibly depleted (Rose, 1993; Meister, 1994).
Protective effect of silymarin on oxidative stress in rat brain by Nencini, C.; Giorgi, G.; Micheli, L. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Localization of a glutathione-dependent dehydroascorbate reductase within the central nervous system of the rat.
DNA damage Associated with ultrastructural alterations in rat ... by Nigro, Marco / Environmental Health Perspectives
 
 
 
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