dendrimer

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dendrimer

[′den·drə·mər]
(organic chemistry)
A polymer with a well-defined core, an interior, and peripheral surface components constructed in a concentric ordered fashion around the core.
A polymer having a regular branched structure. Also known as dendritic polymer; dendron; starburst polymer.
References in periodicals archive ?
avoided the drawbacks of conventional dendrites by avoiding a complex architecturally pure internal dendrimer structure, but still providing a large number of judiciously placed surface functional groups.
Drug molecules can be hidden within the core of the dendrimer or attached to its various branches depending on the sensibilities of the patient.
If you can kill cancer cells without affecting normal cells," says Hongjie Dai, a chemist at Stanford University, "that is the Holy Grail," Among the cast of nanoparticle characters in this work are dendrimers, carbon nanotubes, and liposomes.
VivaGel(TM) is the first example of a product to come from Starpharma's dendrimer-based discovery pipeline, which also includes specific programs in the fields of ADME Engineering(TM) (using dendrimers to control where and when drugs go when introduced to the body), Polyvalency (using the fact that dendrimers can activate multiple receptors simultaneously) and Targeted Diagnostics (using dendrimers as a scaffold to which both location-signaling and targeting groups are added to allow location of specific cell type, such as cancer cells).
Under the terms of this agreement, DNT will supply EMD Biosciences with Priofect transfection reagents based on Priostar proprietary dendrimers for the DNA and siRNA transfection research markets.
Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging.
Kleiman's work focuses on molecules known as dendrimers whose many branching units make them good energy absorbers.
He and his team demonstrated the feasibility of this concept using polyamidoamine dendrimers and showed it was possible to reproducibly achieve highly specific and sensitive assays for important analytes such as creatine kinase MB subunit, thyroxine, and human thyroid-stimulating hormone.
3]-MMT nanocomposites, it was expected that polar--polar interactions would predominate in the formation of nanocomposites; however, some repulsion forces, to some extent, were expected between the polar ends whether on the clay surface or that of the dendrimers [DE.
A collaborative research study demonstrated that steroids attached to dendrimers targeted the cells associated with neuroinflammation leaving the rest of the eye unaffected and preserving vision.