Dephosphorylation(redirected from Dephosphorylating)
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the splitting-off of a phosphoric acid group from a molecule of a compound containing phosphorus. Some unstable organic phosphorus compounds can undergo spontaneous dephosphorylation, but in living organisms dephosphorylation proceeds primarily with the participation of enzymes. Dephosphorylation brought about by kinases (creatine kinase, glucokinase, and so on) leads to the transfer of the phosphoric acid group to other compounds. Dephosphorylation that is catalyzed by phosphorylases (phosphoamidases) results in the formation of free phosphoric acid. The differentiation among the various types of fermentative dephosphorylation is to some extent arbitrary.