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depurination |
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depurination [dē‚pyu̇r·ə′nā·shən] (biochemistry) Detachment of guanine from sugar in a deoxyribonucleic acid molecule. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 2] can interact with DNA and, in turn, lead to depurination of DNA--a potential mutagenesis event (Cavalieri et al. 25 N HC1 for 10 minutes to allow partial depurination and cleavage of large fragments, in denaturation solution composed of 0. This depurination ultimately results in the inhibition of protein synthesis within intoxicated cells (Figure 1B). |
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