Dextran

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dextran

[′dek ‚stran]
(biochemistry)
Any of the several polysaccharides, (C5H10O5)n , that yield glucose units on hydrolysis.

Dextran

 

(C6H10O5)n, a polysaccharide of bacterial origin, a polymer of glucose. The molecular weight can be as high as 10,000,000. In the linear part of the dextran molecule the glucose residues are joined by bonds between the first and sixth carbon atoms; branching is due to bonds between the first and fourth, first and third, and first and second atoms. Dextran is obtained by growing microorganisms of the genus Leuconostoc in an artificial culture medium. Dextran, in the form of a partially hydrolyzed solution with not less than 90 percent 1.6 linkages and a molecular weight of about 60,000 is used clinically as a blood plasma substitute. The preparation provides for a normal osmotic pressure corresponding to that of blood. Modified dextran, so-called Sephadex, is used in chromatography.

References in periodicals archive ?
Of the 2 iron dextrans available, the high molecular weight formulation (Dexferrum) should be used only with caution, based on the preponderance of published data.
Dextrans are sugar molecules linked together into long chains that improve the texture and taste of the sourdough and help keep the bread fresh.
Results with these and other dextrans [9] suggest that the porous walls behave as molecular sieves, passing the smaller dextrans and excluding the larger.
She pointed out that the new dextrans may act as so-called "prebiotics," non-digestible food ingredients that stimulate the growth or activity of bacteria in the digestive system which are beneficial to health.
Here we introduce a gycidyl derivatized dextran hydro-gel.
DES6 is a member of the sulfated dextran family of compounds that attach to the surface of a virus's coat and prevent it from infecting target cells.
23 by light scattering experiments, for sufficiently high degrees of modification, amphiphilic dextrans are not under the form of isolated macromolecules but involved in dense aggregates.
President George Usher said that tests completed at the University of Alberta have shown that Usherdex 4, the company's proprietary form of dextran, actually thins mucus in the lungs, an important strategy for fighting cystic fibrosis.
Some biopolymers that have worked in this application include the celluloses, starches, alginates, caseinates, gelatines and dextrans, which often exhibit phase separation in foods.
With the loosest gel (corresponding to G-84) dextrans with [M.
An example of EPS is the use of LAB dextrans or polymers of alpha(1-6)-linked D-glucose residues as additive.
The enzyme converts cane or beet sugar to alternans, a class of low-calorie or noncaloric dextrans.