The four stereoisomers can be grouped into two pairs of enantiomers, resulting in two diastereomers
(RR + SS and RS + SR).
Therefore, we assume that the 2 closely eluting substances (M17 and M20) are diastereomers
of 2'-hydroxy-XLR-11 glucuronide, whereas the third compound eluting at 9.
It is ideal for structurally similar compounds including chiral entities, diastereomers
, enantiomers, positional isomers and structural analogs.
OBJECTIVES: In the present study we investigated interaction energies between TBECH diastereomers
([alpha], [beta], [gamma], and [delta]) and the hAR, and their ability to activate the receptor and induce prostate-specific antigen (PSA) expression in vitro.
Other subjects covered include synthesis and electronic properties of assemblies of diastereomers
of nickel II complexes with tetracyanometalates, synthesis of functionalized pyrazoles, stereochemical aspects of interaction between some monosaccharides and l-alpha-amino acids in aqueous solutions, and challenges in carbohydrate chemistry.
As a result, a new chiral center is formed, and in respect to the given chirality in the backbone, the two possible N-configurations result in two possible diastereomers
Progress towards identification of the two major diastereomers
made at room temperature, and the structure of the new product will be described.
Gilliland, Structure of the Xenobiotic Substrate Binding Site of a Glutathione S-Transferase as Revealed by X-ray Crystallographic Analysis of Product Complexes with the Diastereomers
of 9-(S-Glutathionyl)-10-Hydroxy-9,10-Dithydrophenanthrene, Biochemistry 33 (5), 1043-1052 (1994).
In the absence of Cu, the bisozaxoline-modified bisthiophene cyclizes without any control of stereochemistry, giving equal mixtures of the (S,S)-(R,R) and (S,S)-(S,S) diastereomers
Since the rearrangement product (shown to be an alpha-glycoside) was a mixture of two diastereomers
only, it was possible to separate them and obtain both enantiomers of our starting [beta]-lactam, Glycals can also be used for conversion to cyclopropyl derivatives.
It requires converting the enantiomers in a racemate to a pair of diastereomers
, or isomers that have different solubilities.
Some of these molecules, including silybin and isosilybin, are naturally present as diastereomers
(A and B), but silychristin may also exist in the diastereomeric form (Lee et al.