For example, since its discovery in 1965, the renowned Tsuji-Trost reaction has been widely exploited in synthetic organic chemistry for the diastereoselective
and enantioselective transfer of allyl groups to various carbon and heteroatom nucleophiles.
The first examples for preparative-scale enantioselective or diastereoselective
epoxide hydrolyses using microorganisms.
They have focused this volume on strategies for performing catalytic enantioselective FC alkylation (up to July 2008), with a collection of more representative diastereoselective
approaches reported in one chapter.
Examples of specific topics include nitrogen-containing organofluorine compounds through metathesis reactions, highly diastereoselective
anodic fluorination, functional compounds based on hypervalent sulfur fluorides, synthesis of macrolactam marine natural products using fluorous protecting groups, solvent-peptide interaction in fluoroalcohol-water mixtures, and synthesis and conformational analysis of fluorine-containing oligopeptides.
At ICOS 16, Thompson will present work on novel diastereoselective
complexation reactions that generate dipyrromethene helicates with > 99 percent selectivity, as well as novel methodology by which to prepare functionalized pyrroles.
Synthetic Methods I - Chiral Pool and Diastereoselective
Asymmetric Synthesis Of Hcvand Hpv Drug Candidates On Scale: The Choice Between Enantioselective And Diastereoselective
Aldol Reaction with Lithium Enolate.
Starting from the key concepts of asymmetric synthesis diastereoselective
methods, asymmetric catalysis) the focus then shifts to its application to the synthesis natural products and industrial processes.