Diethyl Ether

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diethyl ether

(organic chemistry)
C4H10O A colorless liquid, slightly soluble in water; used as a reagent and solvent. Also known as ethyl ether; ethyl oxide; ethylic ether.

Diethyl Ether


(also ether), (C2H5)2O, the most important ether.

Diethyl ether takes the form of a colorless, mobile liquid with a characteristic odor. It has a melting point of – 116.2°C, a boiling point of 34.6°C, and a density of 0.713 g/cm3 at 20°C. Miscible in all proportions with alcohol and many other organic solvents, it is only 6.6-percent soluble in water at 20°C. It readily dissolves fats. Diethyl ether forms an azeotropic mixture with water; the mixture is 98.74-percent diethyl ether, and it has a boiling point of 34.25°C. Diethyl ether is highly flammable, and it forms explosive mixtures with air in concentrations of 1.71–48.0 percent by volume. Upon storage, it is slowly oxidized by atmospheric oxygen to form explosive peroxide compounds.

Diethyl ether is produced from ethyl alcohol at a temperature of 130°–140°C by the action of sulfuric acid—hence, its trivial name in Russian, sernyi efir (sulfuric ether). It may also be produced at 200°–250°C by the vapor-phase dehydration of ethyl alcohol over aluminum oxide (Al2O3) or potassium alums. Diethyl ether is used in industry as a solvent and extracting agent—for example, in the production of powders, motion-picture film, and photographic film. It also has various laboratory uses (seeGRIGNARD REACTION).

In medicine, two grades of diethyl ether are used—medicinal and highly purified. The former is usually applied externally or used for the preparation of tinctures and extracts; it is occasionally taken internally for vomiting. The latter is inhaled as an anesthetic before surgery or sometimes taken as an enema in the form of an oil to reduce pain during childbirth.

The maximum permissible concentration of diethyl ether vapor in the air is 0.3 mg per liter.

References in periodicals archive ?
The samples were extracted with 4 mL of diethyl ether by shaking for 15 min and centrifuging for 5 min at 1200g.
aeruginosa was the most sensitive against DCM extract (15 mm) and minimum of 5 mm were recorded in diethyl ether and n-butanol extracts against Klebsiella oxytoca and P.
The white solid was dissolved in toluene and treated with diethyl ether twice, and then dried under vacuum.
By comparing the extractable plasticizer content obtained from diethyl ether extraction experiments with the percent plasticizers excluding TMPTMA in each formulations, it can be concluded that little amount of nonreactive plasticizer was chemically bound to the fused polymer.
After the mixture reacted for 15 min at room temperature, 2 mL of water was added; the mixture was extracted with 2 mL of diethyl ether.
Extraction was performed three times with 5 mL of diethyl ether and then five times with 5 mL of THF.
Vinylbenzyl n-alkyldimethylammonium (n = 12, 18) chloride was synthesized by the reaction of vinylbenzyl chloride with DDA or ODA (one half stoichiometric excess) in diethyl ether at ambient temperature, as described elsewhere (15).
2%) was carried out at 80[degrees]C for 3 days giving a polymer solution, which after cooling to room temperature was poured into a large amount of diethyl ether.
The diethyl ether phase dehydrated over anhydrous sodium sulfate, filtered and evaporated under vacuum at 30[degrees]C and then derivatized to trimethylsilyl (TMS) ether for subsequent analyses by GC.
albicans, followed by extraction of steroids into diethyl ether and analysis of trimethylsilyl derivatives showed the presence of testosterone (~0.
Tenders are invited for Supply of the under-mentioned goods/articles:Pet Ether solvent, Ethyl acetate, Acetone, Dichloromethane (DCM), THF DMSO DMF, Diethyl ether, Ethylene glycol, NaCl, Sodium Borohydride, Copper sulfate Stannous Chloride dehydrate, Manganese dioxide, 4-Chloro benzyl chloride, Sodium sulfate Silica Gel (60-120 Mesh) for column chromatography, Selenium Powder Bromine Ampules, Phthalimide Thiourea, Triethyl amine, Sodium sulfide Acetonitrile HPLC Grade Silica gel TLC Plate pre-coated on Aluminium Sheet F254 (Catalogue no: 1.
0 g, 12 mmol) was transferred to the flask and dissolved in dry diethyl ether (20 mL).