| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 3,907,672,824 visitors served. |
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
Diisopropyl Fluorophosphate |
Also found in: Medical, Wikipedia | 0.01 sec. |
|
|
Diisopropyl Fluorophosphate
(iso-C3H7O)2P(O)F, a colorless liquid with a slight odor. Melting point, −82°C; boiling point, 67.5°C (12 mm Hg); density, 1.0682 g/cm3 (20°C); and refractive index nD20, 1.3832. Diisopropyl fluorophosphate is slightly soluble in water (1.5 percent) but is readily soluble in organic solvents. Water hydrolyzes it very slowly (reaction of an autocatalytic nature), but it reacts vigorously with alkalis and aqueous solutions of ammonia and amines. It is prepared by the action of potassium fluoride on diisopropyl chlorophosphate. Diisopropyl fluorophosphate causes convulsions, paralysis, and miosis (contraction of the pupil of the eye). A concentration of approximately 0.08 mg// will produce strong miosis. Diisopropyl fluoro-phosphate is used in the physiological and pharmacological studies of the nervous system and as an inhibitor of numerous enzymes in enzymological research. REFERENCESSartori, M. “Novoe v khimii boevykh otravliaiushchikh veshchestv.” Uspekhi khimii, 1954, vol. 23, issue 1, p. 62.O’Brien, R. Toksichnye efiry kislot fosfora. Moscow, 1964. (Translated from English.) Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
|
| Mentioned in | ? | References in periodicals archive | ? | Encyclopedia browser | ? | Full browser | ? | |||
|---|---|---|---|---|---|---|---|---|---|---|
No references found | This is likely to play an important role in neuroprotection against organophosphates: forskolin, which stimulates adenylyl cyclase directly, preserves neural cells from the adverse effects of diisopropylfluorophosphate, potentially by promotion of differentiation, which up-regulates acetylcholinesterase itself (Curtin et al. Agence de Cooperation Culturelle et Techniques, Paris Aron Y, Kone PP, Simaga A (1986) Les serpents en Cote d'Ivoire: Etude biologique in Resume des communications des premieres journees scientifiques, FAST--Abidjan, p 63 Barstad JAB (1956) The effect of d-turbocurarine on the neuro-muscular blocks caused by diisopropylfluorophosphate and acetylcholine. Ahlbom and colleagues exposed neonatal mice to a single oral dose of the organophosphate diisopropylfluorophosphate on either postnatal day 3, 10, or 19. |
Diisopropylfluorophosphate |
Diisatogen DIISD DIISM diisobutyl ketone Diisobutylaluminium hydride Diisobutylene Diisobutylene Diisobutylphthalate Diisocyanate Diisocyanate Diisocyanate diisodecyl adipate Diisodecyl Phenyl Phosphite Diisodecyl Phthalate Diisodecyl Phthalate Diisononyl Phthalate Diisopropanolamine Diisopropanolamine diisopropyl Diisopropyl azo dicarboxylate Diisopropyl Biphenyl Diisopropyl ether Diisopropyl ether Diisopropyl fluorophosphate Diisopropyl Iminodiacetic Acid Diisopropyl Methylphosphonate Diisopropyl phosphorofluoridate Diisopropyl phosphorofluoridate Diisopropylcarbodiimide Diisopropylethylamine Diisopropylfluorophosphate DiisopropylnaphthaleneDiisopropyltryptamine DIISP Diisque DIISR DIISS DIIT diiudicare DIIVS DIJ DIJA DIJEN Dijeredoo Dijeredoo Dijeridooo Dijeridooo Dijeridu Dijeridu DIJF DIJHRO Dijibouti Dijibouti DIJIN Dijks Digital Media Design Dijkstra's guarded command language Dijlah Dijlah DIJOA Dijon Dijon | |||||||
| Encyclopedia |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup |
|---|