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Colorless crystals; melting point, 238°-240°C. It is soluble in alcohol, ether, and solutions of alkalies. With nickel salts it yields a red insoluble precipitate of nickel dimethylglyoximate, (C4H7O2N)2Ni, which is a chelate compound. Because of this, dimethylglyoxime is used for the qualitative and quantitative determination of nickel. In 1905, L. A. Chugaev suggested the use of dimethylglyoxime as a specific reagent for nickel. Dimethylglyoxime is made by treating diacetyl with hydroxylamine.