discodermolide

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discodermolide [‚disk·ə′dər·mə‚līd]

(pharmacology)

A polyketide isolated from deep-water sponges of the genusDiscodermiathat is a potent antitumor agent which inhibits the proliferation of cancer cells by interfering with the cell's microtubule network.

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No references found			Natural products effective against certain cancers have been identified: bryostatin from the colonial bryozoan, ecteinascidin from ascidians or sea squirts, and discodermolide from deep-sea sponges. Oceans and human health: a new era of environmental opportunities by Baden, Daniel G. / Environmental Health Perspectives Discodermolide has been shown by researchers to inhibit cancer cells by the same mechanism as paclitaxel (the active ingredient in Taxol(R)), but also is effective against paclitaxel-resistant tumors. KOSAN GETS NCI GRANT TO DEVELOP ANTI-CANCER AGENT PRODUCTION by Biotech Business Discodermolide has been shown by researchers to inhibit cancer cells by the same mechanism as paclitaxel (the active ingredient in Taxol(R)), but also is effective against paclitaxel-resistant tumors. Kosan Receives NCI Grant to Develop Production Method for Promising ... by Business Wire			dischronation discifloral disciform Discinacea disciple Disciples of Christ Disciplinary Arrest Disciplinary Code Disciplinary Codes Disciplinary Liability Disciplinary Penalties Disciplinary Units Discipline Discipline, Labor Discipline, Military Discipline, Party Discipline, State disclaimer disclimax disco discoaster discoblastula discocephalous discoctaster discodactylous discodermolide discogastrula Discoglossidae Discognathichthys discoid Discoidal Cleavage Discoidiidae Discolichenes Discolomidae discoloration discomfort glare discomfort index discomposition discomposition effect Discomycetes discone antenna disconformity disconnect disconnect fitting disconnected set disconnecting means Disconnecting Switch disconnecting trap disconnector disconnector release Discontinuity			Disco fries Disco Interacting Protein 1 Disco Mixing Club Disco music Disco music Disco Night Culture Disco Related Injury disco- disco- Discoast discoaster Discoblastic discoblastula discoblastula discoboli Discobolos Discobolus Discoccupazione Discocephali discocephalous Discocotyle Discocotyle sagittata discoctaster discocyte Discodactyl Discodactylia Discodactylous Discodactylous discodermolide Discodianism discoed discoed discoes discoes discogastrula discogenic Discogenic Low Back Pain discogenic pain Discoglossidae Discoglossidae Discognathichthys discogram discographer discographer discographers discographers discographic discographic discographical discographical discographies discographies discography discography Discography (Albums, Singles, Maxis, Promo CDs, DVDs) Discography (Albums, Singles, Maxis, Promo CDs, DVDs) Discography jennifer lopez Discoherent discoid

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