distal convoluted tubule

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distal convoluted tubule

[′dist·əl ‚kän·və′lüd·əd ′tü·byül]
(anatomy)
The portion of the nephron in the vertebrate kidney lying between the loop of Henle and the collecting tubules.
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Recent work revealed that secretion from renal tubule epithelial cells occurs primarily from the distal tubule for TIMP-2 and the proximal tubule for IGFBP7.
Tubulo-glomerular feedback is a normal intra-renal mechanism whereby increased solute delivery to distal tubule results in afferent arteriolar vasoconstriction.
In the distal tubule incomplete concentration of intraluminal fluid (urine) occurs at the cost of K+ loss.
Brief report: Liddle's syndrome revisited – A disorder of sodium reabsorption in the distal tubule.
Gitelman's syndrome (GS) is an inherited hypokalemic salt-losing tubulopathy with secondary hyperaldosteronism that affects the thiazide-inhibitable sodium-chloride cotransporter (NCCT) of the distal tubule, making its presentation similar to that of treatment with thiazide diuretics.
2 A-B) shows Bowman's capsule surrounded renal Glomerulus (G), and separated by a distance of Urinary space (U S), also showing Proximal tubule (PT) and Distal tubule (DT).
A large percentage of magnesium is reabsorbed paracellularly in the thick ascending limb, with a smaller transcellular flux in the distal tubule (1).
Specific diuretics Class Drug Comments Thiazide Chlorothiazide Chlorthalidone Thiazide-like in action, not in structure Hydrochlorothiazide Prototypical drug Hydroflumethiazide Indapamide Thiazide-like in action, not in structure Methyclothiazide Metolazone Thiazide-like in action, not in structure Polythiazide Loop Bumetanide Ethacrynic acid Furosemide Torsemide K+-sparing Amioloride Distal tubule [Na.
Among specific topics are lysosomal acidification mechanisms, a new look at electrolyte transport in the distal tubule, autophagy in pulmonary diseases, and interaction between sperm and egg.
The distal tubular acidosis decreases the secretion of H + and is characterized by an inability of the distal tubule to lower urine pH <5.
Disintegration of glomerulus, proximal tubule and necrosed hematopoietic tissues with disorganized glomerular tuft, distal tubule and pycnotic nuclei were noted at 75 mg/L (Fig.