Disulfiram

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disulfiram

[di′səl·fə‚ram]
(pharmacology)
C10H20N2S4 A drug used to treat alcohol abuse that blocks the metabolism of acetaldehyde, the major metabolite of ethanol, causing a rapid buildup of acetaldehyde and a severe physiological syndrome intended to prevent or modify further immediate drinking behavior. Also known as Antabuse.

Disulfiram

 

(also teturamin, Antabuse), a drug used to treat alcoholism. Disulfiram inhibits the oxidation of alcohol, causing acetic aldehyde to accumulate. As a result, the consumption of alcohol leads to such symptoms as sensation of heat, tightness in the chest, heart palpitations, anxiety, and vomiting. Disulfiram is taken orally in the form of tablets. Treatment is first undertaken in a hospital.

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