Therefore, HL-60 cells were treated with this abietane diterpene
and the redox status was monitored by the oxidation-sensitive fluorescent dye [H.
Levels of the cholesterolelevating diterpenes
cafestol and kahweol in various coffee brews.
According to the characteristics of NMR spectra and other physico-chemical data of compound 2, we concluded that this compound is coincided well with henrilabdane B, a diterpene
also isolated from Chloranthus henryi (Li et al.
The drug has the effect of reducing blood pressure in animal experiments, due to the diterpenes
it contains of the andromedan type (grayanotoxins).
A small sampling of specific topics includes: herbal drugs and the role of chromatographic analytical methods, HPLC of carbohydrates, application of HPLC in coumarin analyses, HPLC analysis of diterpenes
, secondary metabolites and amino acid derivatives, and analysis of polyacetylenes.
From the resinous wood of the plant, a number of diterpenes
have been reported, of which several exhibited anti-tumor promoting activity in vivo in a two-stage carcinogenesis test of mouse tumor using 7,12-dimethylbenz[a]-anthracene (DMBA) as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter (Konishi et al.
From other plants of the genus Hyptis various chemical compounds such as flavonoids, diterpenes
e sesquiterpenes with biological and pharmacological activities have been isolated (10-13).
It has been reported that the antioxidative effect is mainly due to phenolic components, such as flavonoids , phenolic acids, and phenolic diterpenes
As several antimicrobial cleorodane diterpenes
and other compounds have previously been isolated from the genus (19).
Rosemary: It contains some of the most promising active agents, including rosmarinic acid, and diterpenes
ursolic acid, carnosic acid, carnosol, oleanolic acid, hinokiol and seco-hinokiol, rofficerone, and amyrenones, which, due to their reported strong antioxidant, anti-inflammatory and tyrosinase inhibiting properties (13), deserve further interest in their skin anti-aging applications.
These two diterpenes
(cholesterol like substances) are specific to coffee, but the amount present varies.
Previous work on the phytochemistry of Eremophila species demonstrated the presence of unusual diterpenes