However, a highly divergent sequence
of DENV-1, which was isolated from a patient who had vacationed in Brunei, was recently reported (7).
Basic Local Alignment Search Tool searches to GenBank with the --650 bp of unambiguous mtCOI sequence from the two divergent sequences
lacking overlapping peaks indicated these sequences had 93% identity to bases 1-542 of two m-mtCOI haplotypes from Mytella charruana reported by Alves et al.
Finally, seventeen divergent sequences
, representing each of the families/taxa were selected to study the specific regions of positive vis-a-vis negative selection.
To remove highly divergent sequences
, BLASTCLUST (http://toolkit.
The scientists plan to "match the DNA sequence of the passenger pigeon with that of its close relative, the band-tailed pigeon" and "stamp out the divergent sequences
from the band-tailed pigeon genome and replace them with synthesized passenger pigeon genetic material.
It also implies that recombination has a significant impact on the generation of diversity in HIV-1, bringing together new combinations of quite divergent sequences
, and perhaps enabling evolutionary "leaps" that are not achievable by simple accumulation of substitutions.
A contribution to the theory of divergent sequences
The apparently higher levels of variation found among ORFs within genotype M is mostly caused by the comparatively divergent sequences
obtained from Pteropus vampyrus (NiV/MY/BA/2010/MY; accession no.
Assay 1 (Table 1) was replaced by assay 2 (Table 2) after the characterization of additional THV strains indicated divergent sequences
between multiple overlapping contigs in these 6 regions indicated at least 2 different strains.
Primers directed to more divergent sequences
, such as the dsb gene, should be utilized in place of, or in addition to, 16S rRNA gene PCR (14).
The most divergent sequences
differ by 24 nt (A/NT/60/68/29C vs.