hybridization probe

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hybridization probe

[‚hī·brəd·ə′zā·shən ′prōb]
(cell and molecular biology)
A small molecule of deoxyribonucleic acid or ribonucleic acid that is radioactively labeled and used to identify complementary nucleic acid sequences by hybridization.
References in periodicals archive ?
CGI's primary focus is to develop and bring to market DNA probes for oncology, providing the cancer community with better tools for diagnosing and monitoring the disease status (including evaluating treatment protocol efficacy) of Lymphomas, Leukemias, Multiple Myeloma, and Cervical Cancer.
James Peacock and his colleagues at the Commonwealth Scientific and Industrial Research Organization in Canberra used DNA probes to identify the hemoglobin gene in the non-nodulating plant, and confirmed by the presence of messenger RNA and protein that the hemoglobin gene was indeed active.
The UroVysion Bladder Cancer Recurrence Kit is the first and only FDA-cleared molecular urine cytology test that uses DNA probes to identify chromosomal abnormalities in patients previously diagnosed with bladder cancer (chromosomal change is the earliest event associated with cancer).
Using dozens of DNA probes that attach to specific genetic sequences, the scientists compared the structures of Y chromosomes from an XX male and an XY female.
The CodeLink bioarray product line for gene expression profiling and determining genetic variation features a unique three-dimensional matrix that improves and simplifies the binding of DNA probes on the array.
Still more evidence that Xp21 is the correct genetic street comes from single-stranded DNA probes that attach to and flag only those RNA or DNA sequences that are complementary with the probe.
The Applied Biosystems Expression Array System is based on highly sensitive, chemiluminescent technology for gene expression detection and incorporates DNA probes that are each approximately 60 base pairs long.
In one type of third-generation test, DNA probes use one side of the virus's double helix to seek out its complementary half.
In addition, Compugen will design a genome-wide collection of DNA probes for Novartis.
Public Health Labs Also, the report examines the market applications of DNA Probes, Monoclonal Antibodies, Immunoassays, IT and other technologies; profiles leading suppliers and recent market entrants developing innovative technologies and products; and identifies emerging business expansion opportunities, alternative market penetration strategies, market entry barriers and risks, and strategic planning issues and concerns.
These experiments," the scientists say, "suggest that DNA probes made from Leishmania kDNa [kinetoplast DNA] may be useful tool for diagnosing leishmaniasis and predicting the severity of the disease.
DNAPrint kits use small DNA probes to query specific single nucleotide polymorphisms (SNPs) within an individual's genome.