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cadherin |
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cadherin [kad′hir·en] (cell and molecular biology) Any of a family of calcium-dependent cell adhesion glycoproteins that play a fundamental role in tissue differentiation and structure. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The loss of E-cadherin makes a cancer cell resemble a stem cell in its capacity to assume any tissue type, notes University of Pittsburgh pathologist Alan Wells. For cell--cell interaction genes and genes involved in signal transduction, marked increases occurred in annexin A2 (48-fold), nidogen 1 (50-fold), E-cadherin (11-fold), and [beta]-catenin (7-fold) in arsenic-induced HCC. CALCIUM-DEPENDENT STABILITY OF E-CADHERIN DOMAIN 1 AND 2 |
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