cadherin

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cadherin

[kad′hir·en]
(cell and molecular biology)
Any of a family of calcium-dependent cell adhesion glycoproteins that play a fundamental role in tissue differentiation and structure.
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Hicks says, "In our hands, the Multiplex INC combination of E-cadherin and p120 provided additional information informing the differentiation of ductal vs.
E-Cadherin and a-catenin reduction influence invasion but not proliferation and survival in canine malignant mammary tumors.
Quantitative analysis of embryo Cx 43, Cx 45, E-cadherin and [beta]-catenin were run in separate wells and compared with [beta]-actin as an endogenous control.
A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes.
If the link between E-cadherin and a poor response to Tamoxifen can be translated into the clinic, it could have huge implications for many thousands of women with breast cancer around the world, as their therapy could then be tailored much more specifically, and therefore more effectively, to their individual cancer.
arenarum, strong E-cadherin immunoreactivity is detected on the cell surface of the developing Mesonephros proximal tubules (Figures 3a) and a weak immunoreactivity is detected in the collecting ducts and in few undifferentiated mesonephrogenic mesenchymal cells (Figures 3b-c).
The p15 methylation was found to be the most frequent 61 per cent (25/41), E-cadherin was methylated in 39 per cent (16/41) and p16 in 37 per cent (15/41) of the cases.
Currently, there are few reports in the literature regarding the role of cell adhesion proteins, such as E-cadherin (ECAD), and neural cell adhesion molecule (NCAM) in pituitary adenomas, as well as of SLUG, which is an important transcriptional regulator of ECAD.
Pleomorphic LCIS and florid LCIS are morphologic variants of LCIS that have been identified and increasingly studied in the past few decades with the advent and routine use of E-cadherin immunohistochemistry (Table).
La hipermetilacion del gen CDKN2B o p15 ocurre en el 80% de los pacientes estudiados a nivel internacional (15) y el gen E-cadherin puede asociarse a recuentos elevados de celulas leucemicas en sangre periferica.