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epidermal growth factor
(redirected from EGF)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.04 sec.
epidermal growth factor [‚ep·ə¦dərm·əl ′grōth ‚fak·tər]
(physiology)
A polypeptide produced in animals that stimulates and sustains the replication of epidermal cells (of ectodermal or endodermal origin); its human equivalent is urogastrone.


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EGF influences cell proliferation and migration, but no study had looked at the molecule's effect on both behaviors simultaneously.
02 nM) EGF produced a significant increase in transformation response as well as in extracellular signal-regulated protein kinase (ERK), SRE, or AP-1 activation.
Vectibix is an entirely human IgG2 monoclonal antibody that binds with high affinity to EGF receptors.
 
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