Eck

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Related to EPHA2: EPHA4

Eck

Johann , original name Johann Mayer. 1486--1543, German Roman Catholic theologian; opponent of Luther and the Reformation
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Forty-five genes implicated in the CC, including 29 nonsyndromic cataract genes ( AGK , BEST1 , BFSP1 , BFSP2 , CHMP4B , CRYAA , CRYAB , CRYBA1 , CRYBA4 , CRYBB1 , CRYBB2 , CRYBB3 , CRYGC , CRYGD , CRYGS , EPHA2 , FYCO1 , GJA3 , GJA8 , HSF4 , P3H2 , LIM2 , MAF , MIP , NHS , PITX3 , SLC16A12 , TDRD7 , and VIM ) and 16 syndromic cataract genes ( ABHD12 , CNBP , CTDP1 , EYA1 , FTL , GALK1 , GCNT2 , GFER , GJA1 , JAM3 , OPA3 , PAX6 , RAB3GAP2 , SIL1 , SIX6 , and SLC33A1 ), were collected from careful literature and database search.
Adverse events Nausea, vomiting, myelosuppression, edema, headache, indigestion, rash, muscle cramps, bone pain, liver toxicity Characteristic Dasatinib Targets Bcr-Abl (a), SRC kinase, c-KIT, EPHA2, platelet-derived growth factor receptor (PDGFR) [beta] Response rates Complete hematologic response occurred in 37 of 40 patients in chronic phase and 31 of 44 patients in other phases.
When EPHA2 is absent, unphosphorylated proteins accumulate that indicate high levels of cellular stress.