Edman degradation technique

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Edman degradation technique [′ed·mən ‚deg·rə′dā·shən tek‚nēk]

(biochemistry)

In protein analysis, an approach to amino-end-group determination involving the use of a reagent, phenylisothiocyanate, that can be applied to the liberation of a derivative of the amino-terminal residue without hydrolysis of the remainder of the peptide chain.

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