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electroconvulsive therapy
(redirected from Electroconvulsive shock)

   Also found in: Medical, Acronyms, Wikipedia, Hutchinson 0.03 sec.
electroconvulsive therapy in psychiatry, treatment of mood disorders by means of electricity; the broader term "shock therapy" also includes the use of chemical agents. The therapeutic possibilities of these treatments were discovered in the 1930s by Manfred Sakel, a Polish psychiatrist, using insulin; L. J. Meduna, an American psychiatrist, using Metrazol; and Ugo Cerletti and Lucio Bini, Italian psychiatrists, using electric shock. Metrazol and insulin accounted for a very limited number of remissions in cases of schizophrenia. However, the injection of insulin often caused coma, while Metrazol and electric shock resulted in convulsions similar to those of epileptics.

Advances in electroconvulsive therapy (ECT) have made it the standard mechanism of shock therapy. ECT has had unquestionable success with involutional melancholia and other depressive disorders, although it may be ineffective or only temporarily effective. ECT is generally employed only after other therapies for depression, mania, bipolar disorder or schizophrenia have proven ineffective. The administration of anesthetics and muscle relaxants prior to ECT has greatly reduced the risk of injury during the procedure, which is typically administered six to eight times over a period of several weeks. The seizure lasts for up to 20 seconds, and the patient can be up and about in about an hour. Long-term memory loss is the main significant potential side effect; headache and temporary short-term memory loss may occur. Why ECT works, however, is still not fully understood, but it may be the result of neurotransmitters neurotransmitter, chemical that transmits information across the junction ( synapse ) that separates one nerve cell (neuron) from another nerve cell or a muscle. Neurotransmitters are stored in the nerve cell's bulbous end (axon).
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 released in the brain as a result of the seizure.

Bibliography

See A. S. Hermreck and A. P. Thal, The Adrenergic Drugs and Their Use in Shock Therapy (1968); L. B. Kalinowsky and H. Hippius, Pharmacological, Convulsive, and other Somatic Treatments in Psychiatry (1969).


electroconvulsive therapy

 formerly shock therapy

Method of treating psychiatric disorders by inducing shock through electric current. Electroconvulsive, or electroshock, therapy involves passing an electric current through the patient's head between two electrodes placed over the temples and thus causing a convulsive seizure; it was used to treat bipolar disorder and other types of depression. Shock was previously induced by administering increasingly large doses of insulin until the patient was thrown into a brief coma; the so-called insulin-shock therapy was used for the treatment of schizophrenia. Both forms of shock therapy were developed in the 1930s. Their use declined after the introduction of tranquilizing drugs and antidepressants.


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In a paper published in the May 2 Journal of Neuroscience, a team led by Tarique Perera of Columbia University found that electroconvulsive shock therapy, a last-resort treatment for depression in people, boosts neurogenesis in adult monkeys.
Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus.
Once diagnosed, 80 percent of clinically depressed individuals, including older persons, can be successfully treated by medication, psychotherapy, electroconvulsive shock therapy or any combination of the three.
 
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