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electrophile |
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electrophileAtom or molecule that in a chemical reaction seeks an atom or molecule containing an electron pair available for bonding or the negative end of a polar molecule (see covalent bond; electric dipole). In the Lewis electron theory (see acid-base theory) advanced by the U.S. chemist Gilbert Lewis (1875–1946) in 1923, electrophiles are by definition Lewis acids. Examples include the hydronium ion (H3O+), boron trifluoride (BF3), and the halogens fluorine, chlorine, bromine, and iodine in molecular form. See also acid; nucleophile. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| GST catalyzes the conjugation of electrophilic molecules with glutathione to protect macromolecules from damage (Awasthi et al. patent: 6,133,364 Issued: October 17, 2000 Inventors: Werner Obrecht, Thomas Scholl, Peter Wendling, Michael Well and Victor Monroy Assigned: Continental AG Keywords: Gel particles surface has electrophilic centers, coupling agent between the gel particles, improved hysteresis Process of production of pneumatic tire U. Glutathione S-transferases are liver detoxification enzymes that catalyze the addition of glutathione to xenobiotic electrophilic compounds, solubilizing them and labeling them for transport to the kidneys for elimination. |
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