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Any disease of the brain.



a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
Approximately 200 people worldwide have been diagnosed with KCNQ2 epileptic encephalopathy.
550 as an effective treatment to manage hepatic encephalopathy, a debilitating condition that currently has no cure apart from liver transplantation.
The results of the present study suggest that VSL#3 is at least as effective as standard treatment for patients with cirrhosis and minimal hepatic encephalopathy.
Wernicke encephalopathy is an example of the wide range of brain diseases called encephalopathies that are caused by metabolic disorders and toxic substances," said Matthew McCoyd, a neurologist at Loyola University Medical Centre in the US.
stated, "We are very pleased to have this opportunity to add an additional license through NIH-OTT under the '507 Patent' for the furtherance of research and development of target therapeutics to treat head trauma and, more specifically Chronic Traumatic Encephalopathy (CTE).
Pathologic changes developing due to Wernicke's encephalopathy are prominent particularly in the brainstem and hypothalamus, and the characteristic change is subtotal tissue necrosis including neuron, axon and myelin (3).
Professor Peter Hayes, of the Scottish Liver Transplant Unit, said: "Being able to use Targaxan 550 is important as liver disease has been on the rise so we see more cases of hepatic encephalopathy.
Electroencephalography was done and showed moderate encephalopathy of non-specific etiology with no signs of seizures or spikes to suggest Creutzfeld-Jakob disease.
Published in the August issue of the American Journal of Pathology, the study sought to find out more about the early incubation period of bovine spongiform encephalopathy, which is a fatal disease in cattle that causes portions of the cows' brains to turn sponge-like.
A patient with acute neurological complications associated with H1N1 infection was reported to have laboratory-confirmed Hi Ni infection of the respiratory tract and associated seizures, and encephalopathy or encephalitis within 5 d of the onset of influenza-like symptoms, without evidence of an alternative etiology.