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endochondral ossification
(redirected from Endochondral)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
endochondral ossification [¦en·dō′kän·drəl ‚äs·ə·fə′kā·shən]
(physiology)
The conversion of cartilage into bone. Also known as intracartilaginous ossification.


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It is characterised by rhizomelic shortness of the limbs and spinal stenosis, secondary to abnormalities of endochondral ossification.
In addition, Pb has important in vivo effects on endochondral bone formation, as Pb-exposed mice and rats have altered growth plate morphology and decreased longitudinal growth (Gonzalez-Riola et al.
The cartilage component is variable and can show endochondral ossification with bone formation, coarse calcifications, or loosely arranged mature hyaline cartilage.
 
 
 
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