The results of this study provide the magnitude of the understandable data that may be used to convince perimenopausal women with AUB to have early endometrial biopsy and appropriate management to reduce the risk of progression to malignancy.
In another study by Sharma et al, (9) on 120 women undergoing hysteroscopy and endometrial biopsy, there was significant reduction in the mean pain score with the use of oral drotaverine hydrochloride and mefenamic acid compared to paracervical block and intravenous sedation using diazepam.
Others reported that a single endometrial biopsy done during hysteroscopy on days 4-7 of the cycle before the embryo transfer cycle leads to a significant increase in clinical pregnancy and live birth rates (72).
Although EIN is a departure from previous endometrial biopsy classification schema, it is easy to implement and interpret because the criteria are precisely stated and more easily communicated between pathologists when compared with "atypia.
Dilat- ion and curettage is now considered to be an out- dated practice and is replaced by less invasive out- patient evaluation using endometrial biopsy devices and outpatient hysteroscopy guided biopsies.