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endonuclease
(redirected from Endonucleases)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
endonuclease [¦en·dō′nü·klē‚ās]
(biochemistry)
Any of a group of enzymes which degrade deoxyribonucleic acid or ribonucleic acid molecules by attaching nucleotide linkages within the polynucleotide chain.


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Potentially useful restriction endonucleases identified by the virtual digestion analyses were then tested in a PCR/ RFLP agarose gel analysis of the ITS-1 marker in multiple individuals of each species.
They address the move toward a universal platform for autologous stem cell gene therapy and also address adenosine deaminase deficiency, insertion of a transgene into Chromosome 19, site-specific integrating vectors, gene targeting, engineering of homing endonucleases and novel sequence-specific DNA binding and modifying, gene targeting mediated by hyper-dependent adenoviral vectors, and multipotent progenitor cells.
THE MOLECULAR SCISSORS: RESTRICTION ENDONUCLEASES The discovery of restriction endonucleases, one class of deoxyribonucleases, in the late 1960s sparked a revolution in the study of variation at the molecular level.
 
 
 
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