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Enlargement of the spleen.



in medicine, the enlargement of the spleen. Splenomegaly occurs with diseases of the spleen (tumors, cysts, abscesses), with general infections (sepsis, malaria, typhoid fever, typhus), with blood diseases (leukoses, lymphgranulomatos-es), and with liver diseases. The spleen is examined by palpation while the individual is lying on his side; it will not be felt if its size is normal.

Splenomegaly is often the first manifestation of blood disease. In such cases, splenic puncture is performed in order to make an accurate diagnosis. With chronic leukoses, the spleen may occupy most of the abdomen and weigh as much as 8 kg. Splenomegaly is accompanied by disruption of breathing, blood circulation, and the functions of adjacent organs, including the stomach, intestine, and left kidney. Disturbances of splenic blood circulation (thromboses), suppression of hematopoiesis (hypersplenism), and other complications may also occur. The condition is treated by surgically removing the spleen (splenectomy), by irradiating the spleen with gamma rays, and by administering cytostatics and corticosteroids.

References in periodicals archive ?
Efficient stereological approaches for the volumetry of a normal or enlarged spleen from MDCT images.
The symptomatic patient usually presents with left upper quadrant abdominal pain or discomfort with or without fever or enlarged spleen.
Virus particles in the spleen were collected, and the severity of illness was measured by weighing the enlarged spleen.
The disease is marked by an enlarged spleen, anemia, decreased white blood cells and platelets, and myelofibrosis-related symptoms.
Meanwhile, diabetic patient Roy Knight, a retired builder, was wrongly told by the QE in 2006 that he had an enlarged spleen.
erythroblastosis fetalis and congenital syphilis, as an enlarged spleen is more fragile than a normal organ.
Abdelhafit is weighed and tested for kala azar, a little-known disease that would explain his bleeding gums, anaemia and low weight, as well as the swollen stomach disguising an enlarged spleen.
A bout with mononucleosis initially sidelined Oregon punter Jackson Rice for just two days, but an enlarged spleen stemming from the illness led to him sitting out the Ducks' final two regular-season games, Rice said Saturday.
Without the benefit of anaesthesia, he excised the enlarged spleen in a girl of 22 suffering from cirrhosis and ascites.
34,35) We had to do a mini-laparotomy in 3 cases by extension of the periumbilical incision to remove the massively enlarged spleen.
Some babies will have signs of toxoplasmosis at birth, which may include an enlarged liver and jaundice, an enlarged spleen, a low platelet count, a rash, a heart or lung infection, and enlarged lymph nodes.
CIMF is characterized by an enlarged spleen and progressive anaemia.