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epigenetics |
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epigenetics [¦ep·ə·jə¦ned·iks] (genetics) The study of those processes by which genetic information ultimately results in distinctive physical and behavioral characteristics. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 1996) in the 1980s and 1990s led to a greater appreciation of the underlying biochemical principles of epigenetic regulation (Fischle et al. The silencing of key cell cycle control genes and tumor suppressor genes through these two mechanisms of epigenetic regulation have been demonstrated in vitro and in vivo in hematological malignancies and in solid tumors. These solicitations are anticipated to stimulate research directed toward the understanding of the role of epigenetic modulation of gene expression in a variety of diseases and dysfunctions and the modulation of epigenetic regulation by environmental chemicals either alone or in combination with altered nutrition. |
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