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epimerization |
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epimerization [‚e·pim·ə·rə′zā·shən] (organic chemistry) In an optically active compound that contains two or more asymmetric centers, a process in which only one of these centers is altered by some reaction to form an epimer. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| The epimerization strongly decreases the compound's biologic efficacy; the anabolic potency of TbOH-17[alpha] is only about 5% of that of TbOH-17[beta] (9), and the affinity to the recombinant human androgen receptor (rhAR) is reduced to about 4% (10). |
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