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epitope |
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epitope: see immunity immunity, ability of an organism to resist disease by identifying and destroying foreign substances or organisms. Although all animals have some immune capabilities, little is known about nonmammalian immunity. ..... Click the link for more information. . |
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? Mentioned in | ? References in periodicals archive | |
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Mutations that occur within the immunodominant epitopes of hepatitis B surface antigen (HBsAg) allow mutant virus to propagate in the presence of a neutralizing immune response, while wild-type virus is reduced to undetectable levels. The linear IgE-binding epitopes of the Ara h2 allergen have been mapped using overlapping peptides and serum IgE from a population of patients known to be sensitized to peanuts. A useful approach may involve the use of an expression library, whereby the genome of a pathogen is fragmented and the pieces of DNA captured to create a pathogen library that represents most of the T cell epitopes that exist for that pathogen. |
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