Eschweiler-Clarke modification

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Eschweiler-Clarke modification [¦esh‚vīl·ər ¦klärk ‚mäd·ə·fə′kā·shən]

(organic chemistry)

A modification of the Leuckart reaction, involving reductive alkylation of ammonia or amines (except tertiary amines) by formaldehyde and formic acid.

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