Eschweiler-Clarke modification

Eschweiler-Clarke modification

[¦esh‚vīl·ər ¦klärk ‚mäd·ə·fə′kā·shən]
(organic chemistry)
A modification of the Leuckart reaction, involving reductive alkylation of ammonia or amines (except tertiary amines) by formaldehyde and formic acid.