Euchromatin


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euchromatin

[yü′krō·mə·tən]
(cell and molecular biology)
The portion of the chromosomes that stains with low intensity, uncoils during interphase, and condenses during cell division.

Euchromatin

 

(also active chromatin), the portion of the chromatin that retains the uncoiled form of elementary deoxyribonucleoprotein (DNP) threads in the interval between cell divisions (that is, in the interphase), as opposed to the portion of the chromatin known as heterochromatin, which retains the coiled form. Euchromatin also differs from heterochromatin in that it participates in the intensive synthesis of ribonucleic acid (RNA) and contains a larger quantity of nonhistone proteins. Euchromatin contains not only DNP but also ribonucleoprotein granules, which have a diameter of 200–500 angstroms and serve to complete the maturation of the RNA and its transfer into the cytoplasm. Euchromatin contains most of the structural genes of an organism (seeCHROMOSOME).

References in periodicals archive ?
In addition, CDX2 maintains the euchromatin state for IFNT transcription (Sakurai et al.
In the second study, TEM examination revealed marked filopodia and euchromatin nucleus in the experimental group [9].
Several hypotheses have been suggested to explain why these phenotypic anomalies are seen in balanced chromosome rearrangements, lt may be possible that the gene is broken and the position effects of gene or change in euchromatin structure, loss or small deletions or duplications were not seen with normal cytogenetic methods (6).
12) reported that mono- and dimethylated residues were specifically localized at silent domains within the euchromatin and that H3K9 trimethylation was more frequent in pericentric heterochromatin.
Deacetylation of histones by HDAC modifies the chromatin from an open gene-active euchromatin structure to a closed gene-silenced heterochromatin structure, which may reduce the transcription of genes that suppress tumour growth.
The nucleus increased to 50 [micro]m and appeared almost completely transparent, with the euchromatin staining very light blue.
Both of these types of epigenetic modifications work together to remodel the chromatin and partition the genome into two different functional domains-transcriptionally active regions collectively known as euchromatin and transcriptionally inactive regions collectively called heterochromatin.
High GC content is a characteristic feature of active euchromatin and transcriptional activity.
Synergistic increase in chromosomal breakage within the euchromatin induced by an interaction of the benzene metabolites phenol and hydroquinone in mice.
Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice.
Some large hyalinocyte nuclei had abundant euchromatin, and some showed abundant heterochromatin in the central and the peripheral positions.