exonuclease

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exonuclease

[¦ek·sō′nü·klē‚ās]
(biochemistry)
Any of a group of enzymes which catalyze hydrolysis of single nucleotide residues from the end of a deoxyribonucleic acid chain.
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References in periodicals archive ?
It was demonstrated that fpg probes are less sensitive (10"1 target molecules detected) than exo probe assays (10 target molecules detected), suggesting that the Fpg nuclease has slower kinetics in realtime detection than that of exonuclease III (14).
Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III.
The presence of fpg will not reduce the final overall yield of amplified material, in contrast to the use of Exonuclease III in the TwistAmp(TM) exo kit, allowing end point gel analysis, but the kinetics of probe cutting can be slower than that with the exo system.