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exonuclease
(redirected from Exonucleases)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
exonuclease [¦ek·sō′nü·klē‚ās]
(biochemistry)
Any of a group of enzymes which catalyze hydrolysis of single nucleotide residues from the end of a deoxyribonucleic acid chain.


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5 and 5 Gy irradiation was almost identical in the wild-type (WT) A549 and Cter3 cells, implying that hPNK is not required for homologous recombination and that the processing of strand-break termini in this repair pathway is handled by a different set of enzymes including exonucleases and endonucleases, such as the WRN helicase/nuclease and Mre11 exonuclease (36, 37).
There are two types of DNases: exonucleases act on the end of a DNA chain, while endonucleases attack interior linkages.
Accordingly, enzymes called exonucleases pick up where UDGases and other base cutters leave off, excising damaged nucleotides.
 
 
 
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