Kos, "Inhibition of endopeptidase and exopeptidase
activity of cathepsin B impairs extracellular matrix degradation and tumour invasion," Biological Chemistry, vol.
The protein extracts by Flavourzyme as an exopeptidase
did not have significant effect on cell culture.
Non-proteasome proteases have been divided into exopeptidases
and endopeptidases depending on the cleavage position of target proteins.
This avoids MS analysis and interpretation of extremely complex peptide mixtures that might otherwise result from degradation by the omnipresent exopeptidases
This is a protease preparation containing endo-, exopeptidase
and glutaminase that can be used to hydrolyse proteins such as wheat and soya.
Multiple molecular forms of serum amyloid A, related to trimming of the peptide chain by exopeptidase
, have been noted by MALDI- or SELDI-TOF MS (30, 46-50).
dipeptidyl-peptidase IV (DPP IV/CD26; EC 3.
The identity of target glycopeptides was further confirmed through controlled digestion with exopeptidase
These peaks may represent activity of an endoproteinase followed by an N-terminal exopeptidase
The PEG component of macrosubstrates also may serve as a highly effective protecting group against exopeptidase
action to assure that only endoproteinase activity is measured.
Because of its exopeptidase
activity, it has been implicated in the metabolism of metenkephalin (18) and angiotensin (Ang) III (17); its endopeptidase activity is also thought to be involved in neurotensin metabolism (19).